This was in the wake of a year of violent strikes, in his speech at the Mining Indaba in Cape Town.
He also attempted to calm investor fears over the rule of law.
Ramatlhodi told thousands of delegates that the five month strike in the platinum mines in 2014 was unprecedented and the violence that went with it was going to be discouraged.
"Where people break the law we will arrest and charge and send them to jail there is no turning back on that," said Ramatlhodi.
"The five month strike in platinum was an exception that proves the rule and we don't want to see a repeat of that...When the elephants fight it is the grass that suffers."
Ramatlhodi also made assurances that the power problem was being addressed, with the development of nuclear energy and the signing up of private power producers, and also sought to shore up investor confidence.
He said the amendments to the mining bill, which include the separation of oil and gas from mining, would be the key to unlock investment.
"The bearing of our country is respect for the rule of law. Anyone who feels short changed or aggrieved is free to approach the courts," said Ramatlhodi.